In the ever-evolving world of aesthetic medicine, skin boosters have become a game-changer in non-surgical skin rejuvenation. These treatments involve microinjections of active ingredients that enhance skin quality, hydration, and collagen production, effectively jumpstarting the skin to a more youthful state. Imagine hitting the reset button on your skin, turning back the clock in just 15 minutes—with minimal downtime. Who wouldn’t want that?
We get it—needles and skin? Sounds uncomfortable, right? But here’s the good news: skin booster injections are far less intimidating than they seem. Most clinics use ultra-fine 34G needles, which are exceptionally thin and delicate, making the procedure minimally invasive and only mildly uncomfortable. Plus, with the application of topical anesthesia, most patients find the treatment easily tolerable—many even describe it as a quick and simple beauty boost! Skin boosters serve as a must-consider complement to other non-invasive procedures like lasers, radiofrequency (RF), and HIFU, helping to maximize overall skin rejuvenation results.
When it comes to aesthetic treatments, safety is always a top priority—and skin boosters are no exception.
At Ozhean Clinics, we operate in countries with strict regulatory standards, ensuring that all skin booster products meet rigorous FDA (USA), EU (Europe), or KFDA (Korea) certifications. These approvals are backed by extensive clinical studies, proving their effectiveness and safety for skin rejuvenation.
Beyond certification, every product undergoes a meticulous manufacturing process to guarantee sterility and bioactivity throughout its shelf life. This means you can trust that each injection delivers pure, high-quality ingredients designed to enhance your skin safely and effectively.
Among the most popular skin boosters available in Korea, Thailand, Indonesia, Singapore and Malaysia today are:
✔ Profhilo – Known as the ultimate hydrator, Profhilo contains one of the highest concentrations of hyaluronic acid (HA). It spreads beneath the skin like a hydro-lifting treatment, improving elasticity and firmness while delivering deep hydration.
✔ Rejuran Healer – A favorite for skin repair and anti-aging, Rejuran is powered by polynucleotides (PN) derived from salmon DNA. It excels at stimulating skin regeneration, reducing fine lines, and improving skin texture and resilience.
✔ Jalupro – Dubbed the collagen booster, Jalupro combines HA with essential amino acids to restore volume and improve skin elasticity. It’s a great option for reducing wrinkles and reviving dull, aging skin.
✔ Teosyal Redensity 1 – A multi-tasking skin booster, this formula not only hydrates but also brightens the skin with antioxidants, amino acids, and vitamins. It’s ideal for those looking to achieve a radiant, even-toned complexion.
✔ Chanel NCTF 135HA - Also known as Chanel Injections, this luxurious skin booster is formulated with hyaluronic acid (HA) and 59 active ingredients, including vitamins, minerals, amino acids, and antioxidants, to deeply nourish and rejuvenate the skin. Loved for its multi-repair and anti-aging effects, this treatment is for those looking to achieve a naturally luminous, plump, and revitalized complexion.
While each of these treatments delivers unique benefits, Juvelook has been gaining significant popularity in Asia, particularly in Korea, Thailand, Malaysia, and Singapore, due to its superior collagen stimulation properties. But how does it compare to Profhilo, Rejuran, and Chanel injections?
Let’s take a closer look.
Juvelook is a cutting-edge hybrid skin booster designed to stimulate collagen production and deeply hydrate the skin, offering long-term skin rejuvenation. It combines Poly-D,L-lactic Acid (PDLLA), a powerful biostimulator, with non-crosslinked Hyaluronic Acid (HA) to provide both immediate hydration and long-lasting structural improvement. PDLLA works by acting as a scaffold for fibroblasts, encouraging the body to naturally produce new collagen over 12 months. This makes Juvelook an excellent choice for those looking to restore skin elasticity, firmness, and overall youthful vitality.
One of the standout benefits of Juvelook is its ability to gradually enhance skin quality over time, addressing multiple concerns such as fine lines, wrinkles, acne scars, and enlarged pores. As collagen production increases, the skin appears tighter, smoother, and more refined, reducing signs of aging and improving overall texture. Unlike traditional fillers that mainly add volume, Juvelook rebuilds and strengthens the skin from within, ensuring results that look natural and last longer. Whether used as a preventive anti-aging solution or a corrective treatment for textural irregularities, Juvelook delivers a noticeable glow and youthful resilience.
Compared to older collagen stimulators like Sculptra (PLLA) or Radiesse, Juvelook features smaller, spherical PDLLA particles, which significantly reduce the risk of lumps or nodules. This makes the treatment safer and more predictable, providing patients with a smooth and even skin texture without complications. Ideal for individuals seeking collagen stimulation, pore refinement, and acne scar improvement, Juvelook is a game-changing treatment that offers both immediate hydration and long-term skin regeneration. If you're looking for a minimally invasive yet highly effective skin booster, Juvelook could be the ideal solution to revitalize and restore your skin's youthful glow.
Profhilo is a ultra-pure, high-molecular-weight hyaluronic acid (HA) skin booster designed to deliver intense hydration and improve overall skin quality. Unlike collagen-stimulating injectables such as Juvelook, which rely on PDLLA to trigger new collagen formation, Profhilo works by spreading widely under the skin, allowing its moisture-retaining properties to deeply nourish and rejuvenate the skin. This ability to disperse evenly beneath the surface ensures deep hydration across a larger area, making it an excellent choice for individuals seeking a natural, dewy glow with enhanced skin elasticity.
One of the key benefits of Profhilo is its ability to improve skin texture and firmness without adding volume, making it ideal for those who want subtle rejuvenation without the plumped look associated with traditional dermal fillers. Its skin lifting effects are temporary, and its ability to stimulate long-term collagen production is less pronounced compared to Juvelook. Profhilo’s effects are primarily due to its hydrating action. Many users love the instant radiance and smoothness it provides, but some report that the lifting effect gradually fades after about a month, requiring maintenance treatments to sustain the results. However, the high pain level associated with the traditional Profhilo injection technique, which involves large boluses, often makes patients hesitant to return for a second treatment. To improve comfort and patient experience, many doctors have adapted by using smaller boluses, which significantly reduce discomfort and make the procedure more tolerable.
While Profhilo may not provide dramatic lifting or long-term collagen stimulation, it remains one of the top treatments for deep hydration, improved skin elasticity, and a radiant complexion. It is especially beneficial for those with dry, dull, or aging skin seeking a non-invasive skin refresh. Similar to Chanel NCTF 135HA and Teosyal Redensity 1, Profhilo falls under the category of intense hydrators that work by enhancing skin moisture and suppleness.
The key difference, however, lies in molecular weight and spreadability. Chanel and Teosyal Redensity 1 contain lower molecular weight hyaluronic acid, which means they focus more on hydration and antioxidant benefits rather than structural support. As a result, their skin-lifting effects are minimal compared to Profhilo. However, it is important to note that even Profhilo’s lifting effects are temporary, as it lacks the long-term collagen stimulation seen in biostimulators like Juvelook.
Ultimately, all three treatments—Profhilo, Chanel, and Teosyal Redensity 1—are excellent choices for boosting skin hydration and radiance. However, if firming and collagen stimulation are your primary goals, combining them with other collagen-inducing treatments may offer more comprehensive and longer-lasting results.
Rejuran, often referred to as the "Skin Healer," is a unique skin booster formulated with PDRN (Polydeoxyribonucleotide), a powerful ingredient extracted from salmon DNA. Known for its remarkable regenerative and anti-inflammatory properties, Rejuran works at a cellular level to repair and strengthen the skin’s barrier. This makes it an ideal choice for those struggling with damaged, irritated, or sensitive skin, as it helps to soothe inflammation, accelerate tissue repair, and promote overall skin recovery. Unlike conventional hyaluronic acid-based skin boosters that primarily focus on hydration, Rejuran is designed to heal and rejuvenate the skin from within.
One of the standout uses of Rejuran is in post-laser and post-chemical peel recovery. After undergoing procedures that can leave the skin red, sensitive, and compromised, Rejuran helps to speed up healing, reduce downtime, and restore the skin’s natural balance. It is particularly effective for acne-prone skin, as its anti-inflammatory benefits assist in calming active breakouts while repairing acne scars and strengthening the skin’s resilience. Over time, regular treatments with Rejuran can improve skin texture, reduce sensitivity, and enhance overall skin health, making it a go-to option for those seeking long-term skin repair.
However, while Rejuran is highly effective in healing and soothing the skin, its collagen-stimulating effects are relatively mild compared to Juvelook. While Juvelook actively triggers collagen production over time, Rejuran’s primary function is to nurture and restore rather than significantly boost skin firmness. This makes it best suited for individuals looking for skin healing, post-laser recovery, and acne scar improvement, rather than those seeking dramatic lifting or structural enhancement. For those who want both deep skin repair and long-term collagen production, combining Rejuran with collagen stimulators like Juvelook can offer comprehensive skin rejuvenation with superior results.
Chanel Injections (NCTF 135HA), along with Sunekos, Cytocare, and Jalupro, fall under the category of Skin Nutrition Therapy or Amino Acid Replacement Therapy, designed to nourish, hydrate, and revitalize the skin. Unlike traditional skin boosters that rely solely on hyaluronic acid (HA) for hydration, these formulations go a step further by incorporating a powerful blend of amino acids, vitamins, minerals, and antioxidants. This unique combination works to restore skin health at a cellular level, making it an excellent option for those looking to achieve radiant, well-nourished, and deeply hydrated skin.
One of the standout benefits of Chanel Injections (NCTF 135HA) is its ability to brighten the complexion, enhance skin elasticity, and improve overall hydration. By infusing the skin with a cocktail of essential nutrients, this treatment supports cellular repair, reduces oxidative stress, and improves skin texture. Sunekos and Jalupro, on the other hand, focus more on rebuilding the extracellular matrix with their high amino acid content, which aids in skin repair and elasticity. Cytocare, another powerhouse in this category, contains HA and rejuvenating ingredients that work synergistically to provide long-lasting hydration and skin revitalization.
However, while these treatments effectively improve skin radiance, hydration, and overall skin quality, they do not provide collagen stimulation in the same way as biostimulators like Juvelook or Sculptra. Their primary role is to nourish and maintain the skin, rather than induce deep structural changes. For those looking for a natural glow, smoother skin, and an extra layer of hydration, Chanel Injections, Sunekos, Cytocare, and Jalupro are excellent choices. However, for firmer skin, enhanced collagen production, and anti-aging effects, combining these treatments with collagen stimulators may offer the most comprehensive skin rejuvenation results.
| Feature | Juvelook | Profhilo | Rejuran | Chanel Injections |
| Main Effect | Collagen biostimulation | Hydration & elasticity | Skin healing & regeneration | Skin revitalization & glow |
| Composition | PDLLA + HA | Pure HA | PDRN (salmon DNA) | HA + vitamins, amino acids |
| Collagen Stimulation | ⭐⭐⭐⭐⭐ | ⭐⭐ | ⭐⭐ | ⭐ |
| Skin Firming & Pore Refinement | ⭐⭐⭐⭐⭐ | ⭐⭐ | ⭐ | ⭐ |
| Acne Scars & Wrinkles | ⭐⭐⭐⭐⭐ | ⭐⭐ | ⭐⭐ | ⭐ |
| Hydration | ⭐⭐⭐ | ⭐⭐⭐⭐⭐ | ⭐⭐⭐ | ⭐⭐⭐⭐⭐ |
| Best Used With | HIFU, RF, lasers | Juvelook, HIFU | Lasers, microneedling | Any treatment |
While all these boosters offer unique benefits, Juvelook leads the way in collagen stimulation. Here’s why:
✅ Deep Collagen Stimulation – Unlike Profhilo, Rejuran, or Chanel, Juvelook’s PDLLA actively triggers fibroblasts for months, thickening the skin and enhancing skin firmness, pore size, and scars.
✅ Lasting Effects – While Profhilo’s effects fade in a month, Juvelook continues to improve skin quality for up to 12 months.
✅ Safe & Natural-Looking – Unlike previous biostimulators like Sculptra or Radiesse, Juvelook’s microspheres are tiny, reducing the risk of lumps.
✅ Versatile & Complementary – Juvelook can be combined with other boosters like Profhilo (for hydration) or Rejuran (for healing).
Because each skin booster serves different functions, established aesthetic centers in Korea, Thailand, Malaysia, Indonesia and Singapore often combine multiple boosters for customized enhanced skin rejuvenation.
Achieving the best skin rejuvenation results requires a personalized approach, as different skin concerns require targeted treatments. By strategically combining skin boosters, we can harness their individual strengths to create a multi-dimensional treatment plan that addresses hydration, collagen stimulation, and skin repair.
For aging skin and wrinkles, the ideal combination is Juvelook + Profhilo (or Cytocare or Jalupro). Juvelook is a collagen biostimulator that actively promotes skin regeneration, firmness, and wrinkle reduction over time. Pairing it with a hydration-focused booster like Profhilo, Cytocare, or Jalupro ensures that the skin remains plump, elastic, and deeply moisturized. Profhilo disperses extensively beneath the skin, delivering deep hydration and improving elasticity, while Jalupro and Cytocare work to nourish and strengthen the skin. These boosters are enriched with amino acids and antioxidants, which help enhance skin texture, boost resilience, and support collagen production. With their higher concentration of amino acids, they provide essential building blocks for collagen synthesis, promoting firmer, more youthful-looking skin.
For acne-prone skin, a combination of Juvelook and Rejuran works exceptionally well. Juvelook stimulates collagen production, helping to smooth acne scars and refine skin texture, while Rejuran, powered by PDRN (salmon DNA), provides deep healing, reduces inflammation, and strengthens the skin barrier. This combination helps to calm active breakouts, promote post-acne recovery, and leave the skin stronger and more resilient.
Meanwhile, for ultimate hydration, the best combination is Juvelook + Jalupro + Rejuran. Juvelook provides long-term structural support, Jalupro delivers intense hydration with amino acids and HA, and Rejuran enhances repair and skin renewal. This trio ensures maximum skin hydration, healing, and long-lasting radiance, making it the perfect protocol for dry, dull, or sensitive skin in need of deep revitalization.
Ultimately, the best skin booster for you depends on your goals, how much younger you want to look, and, of course, your budget. If deep hydration and a radiant glow are your priorities, Profhilo or Jalupro Injections are excellent choices, delivering intense moisture and improved skin elasticity. For those needing skin repair and recovery, particularly after laser treatments or acne breakouts, Rejuran stands out for its powerful healing and anti-inflammatory properties. However, if you're looking for a long-term anti-aging solution with real collagen stimulation to firm, tighten, and rejuvenate the skin from within, Juvelook is the superior choice. By understanding your specific skin concerns, you can choose the most effective treatment to achieve your desired results.
Ready to start your skin booster journey? Ask Dr. Park to discover how they can work for your skin. Your future self will thank you.
© 2024 Dr ParkJiYoun | All rights reserved.
